miR-19a: An Effective Regulator of SOCS3 and Enhancer of JAK-STAT Signalling

Suppressors of cytokine signalling (SOCS) proteins are classic inhibitors of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. Many cytokines and pathogenic mediators induce expression of SOCS, which act in a negative feedback loop to inhibit further signal transd...

Descripción completa

Detalles Bibliográficos
Autores principales: Collins, Aideen S., McCoy, Claire E., Lloyd, Andrew T., O’Farrelly, Cliona, Stevenson, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718810/
https://www.ncbi.nlm.nih.gov/pubmed/23894411
http://dx.doi.org/10.1371/journal.pone.0069090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718810/
https://www.ncbi.nlm.nih.gov/pubmed/23894411
http://dx.doi.org/10.1371/journal.pone.0069090

Ejemplares similares