Cargando…
miR-19a: An Effective Regulator of SOCS3 and Enhancer of JAK-STAT Signalling
Suppressors of cytokine signalling (SOCS) proteins are classic inhibitors of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. Many cytokines and pathogenic mediators induce expression of SOCS, which act in a negative feedback loop to inhibit further signal transd...
Autores principales: | Collins, Aideen S., McCoy, Claire E., Lloyd, Andrew T., O’Farrelly, Cliona, Stevenson, Nigel J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718810/ https://www.ncbi.nlm.nih.gov/pubmed/23894411 http://dx.doi.org/10.1371/journal.pone.0069090 |
Ejemplares similares
-
HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction
por: Gargan, Siobhan, et al.
Publicado: (2018) -
miR-181b-5p/SOCS2/JAK2/STAT5 axis facilitates the metastasis of hepatoblastoma
por: Lv, Yong, et al.
Publicado: (2023) -
miR-155 meets the JAK/STAT pathway
por: Persson, Jenny Liao
Publicado: (2013) -
miR-150-Based RNA Interference Attenuates Tubulointerstitial Fibrosis through the SOCS1/JAK/STAT Pathway In Vivo and In Vitro
por: Luan, Junjun, et al.
Publicado: (2020) -
The molecular basis of JAK/STAT inhibition by SOCS1
por: Liau, Nicholas P. D., et al.
Publicado: (2018)