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miR-27b Represses Migration of Mouse MSCs to Burned Margins and Prolongs Wound Repair through Silencing SDF-1a

BACKGROUND: Interactions between stromal cell-derived factor-1α (SDF-1α) and its cognate receptor CXCR4 are crucial for the recruitment of mesenchymal stem cells (MSCs) from bone marrow (BM) reservoirs to damaged tissues for repair during alarm situations. MicroRNAs are differentially expressed in s...

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Detalles Bibliográficos
Autores principales: Lü, Mu-Han, Hu, Chang-Jiang, Chen, Ling, Peng, Xi, Chen, Jian, Hu, Jiong-Yu, Teng, Miao, Liang, Guang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718818/
https://www.ncbi.nlm.nih.gov/pubmed/23894385
http://dx.doi.org/10.1371/journal.pone.0068972