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Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation

The membrane remodeling events required for autophagosome biogenesis are still poorly understood. Because PX domain proteins mediate membrane remodeling and trafficking, we conducted an imaging-based siRNA screen for autophagosome formation targeting human PX proteins. The PX-BAR protein SNX18 was i...

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Detalles Bibliográficos
Autores principales: Knævelsrud, Helene, Søreng, Kristiane, Raiborg, Camilla, Håberg, Karin, Rasmuson, Fredrik, Brech, Andreas, Liestøl, Knut, Rusten, Tor Erik, Stenmark, Harald, Neufeld, Thomas P., Carlsson, Sven R., Simonsen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718966/
https://www.ncbi.nlm.nih.gov/pubmed/23878278
http://dx.doi.org/10.1083/jcb.201205129