Targeting 3-phosphoinositide-dependent protein kinase 1 by N-acetyl-cysteine through activation of peroxisome proliferators activated receptor alpha in human lung cancer cells, the role of p53 and p65

BACKGROUND: N-Acetyl-Cysteine (NAC), a natural sulfur-containing amino acid derivative, and peroxisome proliferators activated receptor alpha (PPARα) ligand have been shown to have anticancer properties. However, the mechanisms by which these agents inhibit human non-small cell lung carcinoma (NSCLC...

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Detalles Bibliográficos
Autores principales: Hann, Swei Sunny, Zheng, Fang, Zhao, Shunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720217/
https://www.ncbi.nlm.nih.gov/pubmed/23867003
http://dx.doi.org/10.1186/1756-9966-32-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720217/
https://www.ncbi.nlm.nih.gov/pubmed/23867003
http://dx.doi.org/10.1186/1756-9966-32-43

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