The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops

The catalytic activity of GDP/GTP exchange factors (GEFs) is considered critical to maintain the typically high activity of Rho GTPases found in cancer cells. However, the large number of them has made it difficult to pinpoint those playing proactive, nonredundant roles in tumors. In this work, we h...

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Detalles Bibliográficos
Autores principales: Menacho-Márquez, Mauricio, García-Escudero, Ramón, Ojeda, Virginia, Abad, Antonio, Delgado, Pilar, Costa, Clotilde, Ruiz, Sergio, Alarcón, Balbino, Paramio, Jesús M., Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720258/
https://www.ncbi.nlm.nih.gov/pubmed/23935450
http://dx.doi.org/10.1371/journal.pbio.1001615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720258/
https://www.ncbi.nlm.nih.gov/pubmed/23935450
http://dx.doi.org/10.1371/journal.pbio.1001615

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