Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging

Mitochondrial DNA (mtDNA) mutations lead to decrements in mitochondrial function and accelerated rates of these mutations has been linked to skeletal muscle loss (sarcopenia). The purpose of this study was to investigate the effect of mtDNA mutations on mitochondrial quality control processes in ske...

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Detalles Bibliográficos
Autores principales: Joseph, Anna-Maria, Adhihetty, Peter J., Wawrzyniak, Nicholas R., Wohlgemuth, Stephanie E., Picca, Anna, Kujoth, Gregory C., Prolla, Tomas A., Leeuwenburgh, Christiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720551/
https://www.ncbi.nlm.nih.gov/pubmed/23935986
http://dx.doi.org/10.1371/journal.pone.0069327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720551/
https://www.ncbi.nlm.nih.gov/pubmed/23935986
http://dx.doi.org/10.1371/journal.pone.0069327

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