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Structural and Logical Analysis of a Comprehensive Hedgehog Signaling Pathway to Identify Alternative Drug Targets for Glioma, Colon and Pancreatic Cancer

Hedgehog is an evolutionarily conserved developmental pathway, widely implicated in controlling various cellular responses such as cellular proliferation and stem cell renewal in human and other organisms, through external stimuli. Aberrant activation of this pathway in human adult stem cell line ma...

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Detalles Bibliográficos
Autores principales: Chowdhury, Saikat, Pradhan, Rachana N., Sarkar, Ram Rup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720582/
https://www.ncbi.nlm.nih.gov/pubmed/23935937
http://dx.doi.org/10.1371/journal.pone.0069132