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Lung Macrophages Contribute to House Dust Mite Driven Airway Remodeling via HIF-1α

HIF-1α is a transcription factor that is activated during hypoxia and inflammation and is a key regulator of angiogenesis in vivo. During the development of asthma, peribronchial angiogenesis is induced in response to aeroallergens and is thought to be an important feature of sustained chronic aller...

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Detalles Bibliográficos
Autores principales: Byrne, Adam J., Jones, Carla P., Gowers, Kate, Rankin, Sara M., Lloyd, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720585/
https://www.ncbi.nlm.nih.gov/pubmed/23935964
http://dx.doi.org/10.1371/journal.pone.0069246