Fibrotic Remodeling of the Extracellular Matrix through a Novel (Engineered, Dual-Function) Antibody Reactive to a Cryptic Epitope on the N-Terminal 30 kDa Fragment of Fibronectin

Fibrosis is characterized by excessive accumulation of scar tissue as a result of exaggerated deposition of extracellular matrix (ECM), leading to tissue contraction and impaired function of the organ. Fibronectin (Fn) is an essential component of the ECM, and plays an important role in fibrosis. On...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Maryada, Tiwari, Anil, Sharma, Shweta, Bhoria, Preeti, Gupta, Vishali, Gupta, Amod, Luthra-Guptasarma, Manni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720593/
https://www.ncbi.nlm.nih.gov/pubmed/23935989
http://dx.doi.org/10.1371/journal.pone.0069343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720593/
https://www.ncbi.nlm.nih.gov/pubmed/23935989
http://dx.doi.org/10.1371/journal.pone.0069343

Ejemplares similares