Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α′: implications for pathological roles of CK2 in promoting cancer cell survival

Protein kinase CK2 has emerged as a promising candidate for the treatment of a number of cancers. This enzyme is comprised of two catalytic subunits (CK2 and/or CK2α′) that form complexes with homodimers of regulatory CK2β subunits. While catalytic and regulatory CK2 subunits are generally expressed...

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Detalles Bibliográficos
Autores principales: Turowec, Jacob P., Vilk, Greg, Gabriel, Michelle, Litchfield, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720604/
https://www.ncbi.nlm.nih.gov/pubmed/23599180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720604/
https://www.ncbi.nlm.nih.gov/pubmed/23599180

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