Cargando…

RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy and Platelet Generation

RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and platelet release, in addition to having a role in platelet activation. These processes were previously studied using pharmacological inhibitors...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Aae, Shin, Jae-Won, Wang, Yuhuan, Min, Sang H., Poncz, Morty, Choi, John K., Discher, Dennis E., Carpenter, Chris L., Lian, Lurong, Zhao, Liang, Wang, Yangfeng, Abrams, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720647/
https://www.ncbi.nlm.nih.gov/pubmed/23935982
http://dx.doi.org/10.1371/journal.pone.0069315