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RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy and Platelet Generation
RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and platelet release, in addition to having a role in platelet activation. These processes were previously studied using pharmacological inhibitors...
Autores principales: | Suzuki, Aae, Shin, Jae-Won, Wang, Yuhuan, Min, Sang H., Poncz, Morty, Choi, John K., Discher, Dennis E., Carpenter, Chris L., Lian, Lurong, Zhao, Liang, Wang, Yangfeng, Abrams, Charles S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720647/ https://www.ncbi.nlm.nih.gov/pubmed/23935982 http://dx.doi.org/10.1371/journal.pone.0069315 |
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