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C5a Regulates IL-12(+)DC Migration to Induce Pathogenic Th1 and Th17 Cells in Sepsis
OBJECTIVE: It is well known that complement system C5a is excessively activated during the onset of sepsis. However, it is unclear whether C5a can regulate dentritic cells (DCs) to stimulate adaptive immune cells such as Th1 and Th17 in sepsis. METHODS: Sepsis was induced by cecal ligation and punct...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720656/ https://www.ncbi.nlm.nih.gov/pubmed/23936099 http://dx.doi.org/10.1371/journal.pone.0069779 |