Integrated Analysis of Drug-Induced Gene Expression Profiles Predicts Novel hERG Inhibitors

Growing evidence suggests that drugs interact with diverse molecular targets mediating both therapeutic and toxic effects. Prediction of these complex interactions from chemical structures alone remains challenging, as compounds with different structures may possess similar toxicity profiles. In con...

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Detalles Bibliográficos
Autores principales: Babcock, Joseph J., Du, Fang, Xu, Kaiping, Wheelan, Sarah J., Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720659/
https://www.ncbi.nlm.nih.gov/pubmed/23936032
http://dx.doi.org/10.1371/journal.pone.0069513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720659/
https://www.ncbi.nlm.nih.gov/pubmed/23936032
http://dx.doi.org/10.1371/journal.pone.0069513

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