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Integrated Analysis of Drug-Induced Gene Expression Profiles Predicts Novel hERG Inhibitors
Growing evidence suggests that drugs interact with diverse molecular targets mediating both therapeutic and toxic effects. Prediction of these complex interactions from chemical structures alone remains challenging, as compounds with different structures may possess similar toxicity profiles. In con...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720659/ https://www.ncbi.nlm.nih.gov/pubmed/23936032 http://dx.doi.org/10.1371/journal.pone.0069513 |