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Promoter directionality is controlled by U1 snRNP and polyadenylation signals
Transcription of the mammalian genome is pervasive but productive transcription outside protein-coding genes is limited by unknown mechanisms(1). In particular, although RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive elongation occurs primarily in the se...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720719/ https://www.ncbi.nlm.nih.gov/pubmed/23792564 http://dx.doi.org/10.1038/nature12349 |