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A Novel Role for Tm7sf2 Gene in Regulating TNFα Expression

We have explored the role of Tm7sf2 gene, which codifies for 3β-hydroxysterol Δ14-reductase, an endoplasmic reticulum resident protein, in the sensitivity to endoplasmic reticulum stress and in the resulting inflammatory response. We used mouse embryonic fibroblasts, derived from Tm7sf2(+/+) and Tm7...

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Detalles Bibliográficos
Autores principales: Bellezza, Ilaria, Roberti, Rita, Gatticchi, Leonardo, Del Sordo, Rachele, Rambotti, Maria Grazia, Marchetti, Maria Cristina, Sidoni, Angelo, Minelli, Alba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720723/
https://www.ncbi.nlm.nih.gov/pubmed/23935851
http://dx.doi.org/10.1371/journal.pone.0068017