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A Novel Role for Tm7sf2 Gene in Regulating TNFα Expression
We have explored the role of Tm7sf2 gene, which codifies for 3β-hydroxysterol Δ14-reductase, an endoplasmic reticulum resident protein, in the sensitivity to endoplasmic reticulum stress and in the resulting inflammatory response. We used mouse embryonic fibroblasts, derived from Tm7sf2(+/+) and Tm7...
Autores principales: | Bellezza, Ilaria, Roberti, Rita, Gatticchi, Leonardo, Del Sordo, Rachele, Rambotti, Maria Grazia, Marchetti, Maria Cristina, Sidoni, Angelo, Minelli, Alba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720723/ https://www.ncbi.nlm.nih.gov/pubmed/23935851 http://dx.doi.org/10.1371/journal.pone.0068017 |
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