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A Role for MeCP2 in Switching Gene Activity via Chromatin Unfolding and HP1γ Displacement
Methyl-CpG-binding protein 2 (MeCP2) is generally considered to act as a transcriptional repressor, whereas recent studies suggest that MeCP2 is also involved in transcription activation. To gain insight into this dual function of MeCP2, we assessed the impact of MeCP2 on higher-order chromatin stru...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720725/ https://www.ncbi.nlm.nih.gov/pubmed/23935992 http://dx.doi.org/10.1371/journal.pone.0069347 |