A Role for MeCP2 in Switching Gene Activity via Chromatin Unfolding and HP1γ Displacement

Methyl-CpG-binding protein 2 (MeCP2) is generally considered to act as a transcriptional repressor, whereas recent studies suggest that MeCP2 is also involved in transcription activation. To gain insight into this dual function of MeCP2, we assessed the impact of MeCP2 on higher-order chromatin stru...

Descripción completa

Detalles Bibliográficos
Autores principales: Brink, Maartje C., Piebes, Diewertje G. E., de Groote, Marloes L., Luijsterburg, Martijn S., Casas-Delucchi, Corella S., van Driel, Roel, Rots, Marianne G., Cardoso, M. Cristina, Verschure, Pernette J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720725/
https://www.ncbi.nlm.nih.gov/pubmed/23935992
http://dx.doi.org/10.1371/journal.pone.0069347

Ejemplares similares

Ejemplares similares