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miR-17~92 promotes T follicular helper cell differentiation and represses subset-inappropriate gene expression
T follicular helper (T(FH)) cells are the prototypic helper T cell subset specialized to enable B cells to form germinal centers and produce high-affinity antibodies. We found that miRNA expression by T cells was essential for T(FH) cell differentiation. More specifically, we show that after protein...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720769/ https://www.ncbi.nlm.nih.gov/pubmed/23812098 http://dx.doi.org/10.1038/ni.2642 |