A Proline-Hinge Alters the Characteristics of the Amphipathic α-helical AMPs

HP (2–20) is a 19-aa, amphipathic, α-helical peptide with antimicrobial properties that was derived from the N-terminus of Helicobacter pylori ribosomal protein L1. We previously showed that increasing the net hydrophobicity of HP (2–20) by substituting Trp for Gln(17) and Asp(19) (Anal 3) increased...

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Detalles Bibliográficos
Autores principales: Lee, Jong Kook, Gopal, Ramamourthy, Park, Seong-Cheol, Ko, Hyun Sook, Kim, Yangmee, Hahm, Kyung-Soo, Park, Yoonkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720801/
https://www.ncbi.nlm.nih.gov/pubmed/23935838
http://dx.doi.org/10.1371/journal.pone.0067597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720801/
https://www.ncbi.nlm.nih.gov/pubmed/23935838
http://dx.doi.org/10.1371/journal.pone.0067597

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