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Cardiotrophin-1 Induces Matrix Metalloproteinase-1 in Human Aortic Endothelial Cells

Rupture of an atherosclerotic plaque is a key event in the development of cardiovascular disorders, in which matrix metalloproteinase-1 (MMP-1) plays a crucial role by degradation of extracellular matrix resulting in plaque instability. Cardiotrophin-1 (CT-1), a member of interleukin-6-type proinfla...

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Detalles Bibliográficos
Autores principales: Tokito, Akinori, Jougasaki, Michihisa, Ichiki, Tomoko, Hamasaki, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720803/
https://www.ncbi.nlm.nih.gov/pubmed/23935888
http://dx.doi.org/10.1371/journal.pone.0068801