Identification of small molecules for human hepatocyte expansion and iPS differentiation

Cell-based therapies hold the potential to alleviate the growing burden of liver diseases. Such therapies require human hepatocytes, which, within the stromal context of the liver, are capable of many rounds of replication. However, this ability is lost ex vivo and human hepatocyte sourcing has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Jing, Schwartz, Robert E., Ross, Nathan T., Logan, David J., Thomas, David, Duncan, Stephen A., North, Trista E., Goessling, Wolfram, Carpenter, Anne E., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720805/
https://www.ncbi.nlm.nih.gov/pubmed/23728495
http://dx.doi.org/10.1038/nchembio.1270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720805/
https://www.ncbi.nlm.nih.gov/pubmed/23728495
http://dx.doi.org/10.1038/nchembio.1270

Ejemplares similares