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Identification of small molecules for human hepatocyte expansion and iPS differentiation
Cell-based therapies hold the potential to alleviate the growing burden of liver diseases. Such therapies require human hepatocytes, which, within the stromal context of the liver, are capable of many rounds of replication. However, this ability is lost ex vivo and human hepatocyte sourcing has been...
Autores principales: | Shan, Jing, Schwartz, Robert E., Ross, Nathan T., Logan, David J., Thomas, David, Duncan, Stephen A., North, Trista E., Goessling, Wolfram, Carpenter, Anne E., Bhatia, Sangeeta N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720805/ https://www.ncbi.nlm.nih.gov/pubmed/23728495 http://dx.doi.org/10.1038/nchembio.1270 |
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