The GPVI-Fc Fusion Protein Revacept Improves Cerebral Infarct Volume and Functional Outcome in Stroke

OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Several antiplatelet drugs for the treatment of myoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Goebel, Silvia, Li, Zhongmin, Vogelmann, Jasmin, Holthoff, Hans-Peter, Degen, Heidrun, Hermann, Dirk M., Gawaz, Meinrad, Ungerer, Martin, Münch, Götz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720811/
https://www.ncbi.nlm.nih.gov/pubmed/23935828
http://dx.doi.org/10.1371/journal.pone.0066960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720811/
https://www.ncbi.nlm.nih.gov/pubmed/23935828
http://dx.doi.org/10.1371/journal.pone.0066960

Ejemplares similares