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The GPVI-Fc Fusion Protein Revacept Improves Cerebral Infarct Volume and Functional Outcome in Stroke
OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Several antiplatelet drugs for the treatment of myoc...
Autores principales: | Goebel, Silvia, Li, Zhongmin, Vogelmann, Jasmin, Holthoff, Hans-Peter, Degen, Heidrun, Hermann, Dirk M., Gawaz, Meinrad, Ungerer, Martin, Münch, Götz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720811/ https://www.ncbi.nlm.nih.gov/pubmed/23935828 http://dx.doi.org/10.1371/journal.pone.0066960 |
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