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Quantifying Biomass Changes of Single CD8+ T Cells during Antigen Specific Cytotoxicity

Existing approaches that quantify cytotoxic T cell responses rely on bulk or surrogate measurements which impede the direct identification of single activated T cells of interest. Single cell microscopy or flow cytometry methodologies typically rely on fluorescent labeling, which limits applicabilit...

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Detalles Bibliográficos
Autores principales: Zangle, Thomas A., Burnes, Daina, Mathis, Colleen, Witte, Owen N., Teitell, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720853/
https://www.ncbi.nlm.nih.gov/pubmed/23935904
http://dx.doi.org/10.1371/journal.pone.0068916