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Quantifying Biomass Changes of Single CD8+ T Cells during Antigen Specific Cytotoxicity
Existing approaches that quantify cytotoxic T cell responses rely on bulk or surrogate measurements which impede the direct identification of single activated T cells of interest. Single cell microscopy or flow cytometry methodologies typically rely on fluorescent labeling, which limits applicabilit...
Autores principales: | Zangle, Thomas A., Burnes, Daina, Mathis, Colleen, Witte, Owen N., Teitell, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720853/ https://www.ncbi.nlm.nih.gov/pubmed/23935904 http://dx.doi.org/10.1371/journal.pone.0068916 |
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