Potential Capacity of Aptamers to Trigger Immune Activation in Human Blood

Target specific short single-stranded DNA (ssDNA) molecules, called aptamers, are auspicious ligands for numerous in vivo applications. However, aptamers are synthetic molecules, which might be recognized by the immune cells in vivo and induce an activation of the innate immune system. Thus, immune...

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Detalles Bibliográficos
Autores principales: Avci-Adali, Meltem, Steinle, Heidrun, Michel, Tatjana, Schlensak, Christian, Wendel, Hans P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720859/
https://www.ncbi.nlm.nih.gov/pubmed/23935890
http://dx.doi.org/10.1371/journal.pone.0068810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720859/
https://www.ncbi.nlm.nih.gov/pubmed/23935890
http://dx.doi.org/10.1371/journal.pone.0068810

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