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Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones

Antimicrobial peptides (AMPs) represent a potential new class of antimicrobial drugs with potent and broad-spectrum activities. However, knowledge about the mechanisms and rates of resistance development to AMPs and the resulting effects on fitness and cross-resistance is limited. We isolated antimi...

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Detalles Bibliográficos
Autores principales: Lofton, Hava, Pränting, Maria, Thulin, Elisabeth, Andersson, Dan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720879/
https://www.ncbi.nlm.nih.gov/pubmed/23894360
http://dx.doi.org/10.1371/journal.pone.0068875