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Estimating Effective Population Size from Linkage Disequilibrium between Unlinked Loci: Theory and Application to Fruit Fly Outbreak Populations
There is a substantial literature on the use of linkage disequilibrium (LD) to estimate effective population size using unlinked loci. The [Image: see text] estimates are extremely sensitive to the sampling process, and there is currently no theory to cope with the possible biases. We derive formula...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720881/ https://www.ncbi.nlm.nih.gov/pubmed/23894410 http://dx.doi.org/10.1371/journal.pone.0069078 |