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Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes

Next-generation sequencing has become the most widely used sequencing technology in genomics research, but it has inherent drawbacks when dealing with high-GC content genomes. Recently, single-molecule real-time sequencing technology (SMRT) was introduced as a third-generation sequencing strategy to...

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Detalles Bibliográficos
Autores principales: Shin, Seung Chul, Ahn, Do Hwan, Kim, Su Jin, Lee, Hyoungseok, Oh, Tae-Jin, Lee, Jong Eun, Park, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720884/
https://www.ncbi.nlm.nih.gov/pubmed/23894349
http://dx.doi.org/10.1371/journal.pone.0068824