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Tumor Site- and Stage-Specific Associations between Allelic Variants of Glutathione S-Transferase and DNA-Repair Genes and Overall Survival in Colorectal Cancer Patients Receiving 5-Fluorouracil-Based Chemotherapy

INTRODUCTION: Our retrospective cohort study investigated the effect of tumor site and stage on the associations between the allelic variants of glutathione S-transferase (GST) and DNA-repair genes and overall survival (OS) in CRC patients treated with 5-fluorouracil (5-FU)-based adjuvant chemothera...

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Detalles Bibliográficos
Autores principales: Lai, Ching-Yu, Hsieh, Ling-Ling, Sung, Fung-Chang, Tang, Reiping, Bai, Chyi-Huey, Wu, Fang-Yang, Chiou, Hung-Yi, Yeh, Chih-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720885/
https://www.ncbi.nlm.nih.gov/pubmed/23894404
http://dx.doi.org/10.1371/journal.pone.0069039