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A Conserved Aspartic Acid Is Important for Agonist (VUAA1) and Odorant/Tuning Receptor-Dependent Activation of the Insect Odorant Co-Receptor (Orco)

Insect odorant receptors function as heteromeric odorant-gated cation channels comprising a conventional odorant-sensitive tuning receptor, and a conserved co-receptor (Orco). An Orco agonist, VUAA1, is able to activate both heteromeric and homomeric Orco-containing channels. Very little is known ab...

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Detalles Bibliográficos
Autores principales: Kumar, Brijesh N., Taylor, Robert W., Pask, Gregory M., Zwiebel, Laurence J., Newcomb, Richard D., Christie, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720905/
https://www.ncbi.nlm.nih.gov/pubmed/23894621
http://dx.doi.org/10.1371/journal.pone.0070218