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Aberrant Proliferation in CXCR7+ Endothelial Cells via Degradation of the Retinoblastoma Protein

Angiogenesis is a critical factor in the growth and dissemination of solid tumors. Indeed, tumor vasculature is abnormal and contributes to the development and spread of malignancies by creating a hostile microenvironment. The alternative SDF-1/CXCL12 receptor, CXCR7, is frequently and specifically...

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Detalles Bibliográficos
Autores principales: Totonchy, Jennifer E., Osborn, Jessica M., Botto, Sara, Clepper, Lisa, Moses, Ashlee V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720914/
https://www.ncbi.nlm.nih.gov/pubmed/23894550
http://dx.doi.org/10.1371/journal.pone.0069828