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Aberrant Proliferation in CXCR7+ Endothelial Cells via Degradation of the Retinoblastoma Protein
Angiogenesis is a critical factor in the growth and dissemination of solid tumors. Indeed, tumor vasculature is abnormal and contributes to the development and spread of malignancies by creating a hostile microenvironment. The alternative SDF-1/CXCL12 receptor, CXCR7, is frequently and specifically...
Autores principales: | Totonchy, Jennifer E., Osborn, Jessica M., Botto, Sara, Clepper, Lisa, Moses, Ashlee V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720914/ https://www.ncbi.nlm.nih.gov/pubmed/23894550 http://dx.doi.org/10.1371/journal.pone.0069828 |
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