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Characterization of Rotavirus RNAs That Activate Innate Immune Signaling through the RIG-I-Like Receptors

In mammalian cells, the first line of defense against viral pathogens is the innate immune response, which is characterized by induction of type I interferons (IFN) and other pro-inflammatory cytokines that establish an antiviral milieu both in infected cells and in neighboring uninfected cells. Rot...

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Detalles Bibliográficos
Autores principales: Uzri, Dina, Greenberg, Harry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720929/
https://www.ncbi.nlm.nih.gov/pubmed/23894547
http://dx.doi.org/10.1371/journal.pone.0069825