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Transgenic pigs designed to express human α-galactosidase to avoid humoral xenograft rejection

The use of animals as a source of organs and tissues for xenotransplantation can overcome the growing shortage of human organ donors. However, the presence of xenoreactive antibodies in humans directed against swine Gal antigen present on the surface of xenograft donor cells leads to the complement...

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Detalles Bibliográficos
Autores principales: Zeyland, J., Gawrońska, B., Juzwa, W., Jura, J., Nowak, A., Słomski, R., Smorąg, Z., Szalata, M., Woźniak, A., Lipiński, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720986/
https://www.ncbi.nlm.nih.gov/pubmed/23780397
http://dx.doi.org/10.1007/s13353-013-0156-y