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Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients

Despite the growing understanding of the mechanisms of carcinogenesis, cancers of the central nervous system are usually associated with unfavorable prognosis. The use of an appropriate molecular marker may improve the treatment outcome by allowing early diagnosis and treatment susceptibility monito...

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Detalles Bibliográficos
Autores principales: Majchrzak-Celińska, Aleksandra, Paluszczak, Jarosław, Kleszcz, Robert, Magiera, Marta, Barciszewska, Anna-Maria, Nowak, Stanisław, Baer-Dubowska, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720989/
https://www.ncbi.nlm.nih.gov/pubmed/23661397
http://dx.doi.org/10.1007/s13353-013-0149-x