Cargando…

Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients

Despite the growing understanding of the mechanisms of carcinogenesis, cancers of the central nervous system are usually associated with unfavorable prognosis. The use of an appropriate molecular marker may improve the treatment outcome by allowing early diagnosis and treatment susceptibility monito...

Descripción completa

Detalles Bibliográficos
Autores principales:	Majchrzak-Celińska, Aleksandra, Paluszczak, Jarosław, Kleszcz, Robert, Magiera, Marta, Barciszewska, Anna-Maria, Nowak, Stanisław, Baer-Dubowska, Wanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Human Genetics • Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720989/ https://www.ncbi.nlm.nih.gov/pubmed/23661397 http://dx.doi.org/10.1007/s13353-013-0149-x

Ejemplares similares

DNA methylation analysis of benign and atypical meningiomas: correlation between RUNX3 methylation and WHO grade
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2015)

Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2015)

(+)-Usnic acid modulates the Nrf2-ARE pathway in FaDu hypopharyngeal carcinoma cells
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2021)

Lichen-Derived Depsides and Depsidones Modulate the Nrf2, NF-κB and STAT3 Signaling Pathways in Colorectal Cancer Cells
por: Papierska, Katarzyna, et al.
Publicado: (2021)

Indomethacin and Diclofenac Hybrids with Oleanolic Acid Oximes Modulate Key Signaling Pathways in Pancreatic Cancer Cells
por: Narożna, Maria, et al.
Publicado: (2022)

The Wnt Signaling Pathway Inhibitors Improve the Therapeutic Activity of Glycolysis Modulators against Tongue Cancer Cells
por: Kleszcz, Robert, et al.
Publicado: (2022)

The Senescence Markers p16INK4A, p14ARF/p19ARF, and p21 in Organ Development and Homeostasis
por: Wagner, Kay-Dietrich, et al.
Publicado: (2022)

ABCB1 Is Frequently Methylated in Higher-Grade Gliomas and May Serve as a Diagnostic Biomarker of More Aggressive Tumors
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2022)

Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline
por: Carrasco-Garcia, Estefania, et al.
Publicado: (2015)

The Effect of Novel Oleanolic Acid Oximes Conjugated with Indomethacin on the Nrf2-ARE And NF-κB Signaling Pathways in Normal Hepatocytes and Human Hepatocellular Cancer Cells
por: Narożna, Maria, et al.
Publicado: (2020)

The negative regulators of Wnt pathway—DACH1, DKK1, and WIF1 are methylated in oral and oropharyngeal cancer and WIF1 methylation predicts shorter survival
por: Paluszczak, Jarosław, et al.
Publicado: (2014)

DNA methylation analysis with methylation‐sensitive high‐resolution melting (MS‐HRM) reveals gene panel for glioma characteristics
por: Majchrzak‐Celińska, Aleksandra, et al.
Publicado: (2020)

Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions
por: Klump, B, et al.
Publicado: (2003)

Aberrations of the p14(ARF) and p16(INK4a) Genes in Renal Cell Carcinomas
por: Kawada, Yoichi, et al.
Publicado: (2001)

Combinations of PRI-724 Wnt/β-Catenin Pathway Inhibitor with Vismodegib, Erlotinib, or HS-173 Synergistically Inhibit Head and Neck Squamous Cancer Cells
por: Kleszcz, Robert, et al.
Publicado: (2023)

Polymorphisms in promoter sequences of MDM2, p53, and p16(INK4a) genes in normal Japanese individuals
por: Ohsaka, Yasuhito, et al.
Publicado: (2010)

Immortalization of mouse myogenic cells can occur without loss of p16(INK4a), p19(ARF), or p53 and is accelerated by inactivation of Bax
por: Nowak, Jonathan A, et al.
Publicado: (2004)

INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis
por: Liu, Yan, et al.
Publicado: (2009)

Sodium Butyrate Enhances Curcuminoids Permeability through the Blood-Brain Barrier, Restores Wnt/β-Catenin Pathway Antagonists Gene Expression and Reduces the Viability of Glioblastoma Cells
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2021)

Lichen-derived caperatic acid and physodic acid inhibit Wnt signaling in colorectal cancer cells
por: Paluszczak, Jarosław, et al.
Publicado: (2017)

Effect of Iodine Intake on p14ARF and p16INK4a Expression in Thyroid Papillary Carcinoma in Rats
por: Sun, Ruimei, et al.
Publicado: (2015)

Ratio of Expression of p16(INK4a) to p14(ARF) Correlates with the Progression of Non‐small Cell Lung Cancer
por: Moriyama, Satoru, et al.
Publicado: (2002)

DNA methylation of the p14(ARF), RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients
por: NILSSON, TORBJÖRN K., et al.
Publicado: (2012)

New insights on the regulation of INK4/ARF locus expression
por: Gamell, Cristina, et al.
Publicado: (2017)

The status of CDKN2A alpha (p16(INK4A)) and beta (p14(ARF)) transcripts in thyroid tumour progression
por: Ferru, A, et al.
Publicado: (2006)

Role of p14(ARF) and p15(INK4B) promoter methylation in patients with lung cancer: a systematic meta-analysis
por: Yang, Xinmei, et al.
Publicado: (2016)

Clinical significance of p16(INK4A) and p14(ARF) promoter methylation in renal cell carcinoma: a meta-analysis
por: Ren, Yu, et al.
Publicado: (2017)

Molecular Analysis of Tumor Suppressor Genes, Rb, p53,pl6INK4A, pl5INK4B and p14ARF in Natural Killer Cell Neoplasms
por: Sakajiri, Sakura, et al.
Publicado: (2001)

The effects of fucodian on senescence are controlled by the p16(INK4a)-pRb and p14(Arf)-p53 pathways in hepatocellular carcinoma and hepatic cell lines
por: MIN, EUN-YOUNG, et al.
Publicado: (2014)

Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-κB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo
por: Cykowiak, Marta, et al.
Publicado: (2021)

Transcriptional regulation of INK4/ARF locus by cis and trans mechanisms
por: Farooq, Umer, et al.
Publicado: (2022)

Modulation of Nrf2 and NF-κB Signaling Pathways by Naturally Occurring Compounds in Relation to Cancer Prevention and Therapy. Are Combinations Better Than Single Compounds?
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2021)

Frequency of P16INK4a and P14ARF Genes Methylation and Its Impact on Bladder Cancer Cases in North Indian Population
por: Ali Hosseini, Seyed, et al.
Publicado: (2010)

Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
por: Spitzwieser, Melanie, et al.
Publicado: (2015)

Detection of methylation in the CpG islands of the p16INK4A, RASSF 1A and methylguanine methyltransferase gene promoters in pancreatic adenocarcinoma
por: Paikos, D, et al.
Publicado: (2009)

p53 and p16(Ink4a)/p19(Arf) Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells()()
por: Azzopardi, Stephanie, et al.
Publicado: (2016)

Jun dimerization protein 2 controls hypoxia‐induced replicative senescence via both the p16(Ink4a)‐pRb and Arf‐p53 pathways
por: Nakade, Koji, et al.
Publicado: (2017)

p16(INK4A) and p14(ARF) Gene Promoter Hypermethylation as Prognostic Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma: A Review
por: Al-Kaabi, A., et al.
Publicado: (2014)

Hypermethylation status of DAPK, MGMT and RUNX3 in HPV negative oral and oropharyngeal squamous cell carcinoma
por: dos Reis, Raquel Silva, et al.
Publicado: (2020)

The effect of resveratrol and its methylthio-derivatives on the Nrf2-ARE pathway in mouse epidermis and HaCaT keratinocytes
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_gp2v5rcl0jdfhcb593a9gbuhr7