The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction

Insulin-like growth factor-1 (IGF-1) isoforms are expressed via alternative splicing. Expression of the minor isoform IGF-1Eb [also known as mechano-growth factor (MGF)] is responsive to cell stress. Since IGF-1 isoforms differ in their E-domain regions, we are interested in determining the biologic...

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Detalles Bibliográficos
Autores principales: Mavrommatis, Evangelos, Shioura, Krystyna M., Los, Tamara, Goldspink, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720995/
https://www.ncbi.nlm.nih.gov/pubmed/23712705
http://dx.doi.org/10.1007/s11010-013-1689-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720995/
https://www.ncbi.nlm.nih.gov/pubmed/23712705
http://dx.doi.org/10.1007/s11010-013-1689-4

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