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The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction
Insulin-like growth factor-1 (IGF-1) isoforms are expressed via alternative splicing. Expression of the minor isoform IGF-1Eb [also known as mechano-growth factor (MGF)] is responsive to cell stress. Since IGF-1 isoforms differ in their E-domain regions, we are interested in determining the biologic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720995/ https://www.ncbi.nlm.nih.gov/pubmed/23712705 http://dx.doi.org/10.1007/s11010-013-1689-4 |