An information-gain approach to detecting three-way epistatic interactions in genetic association studies

BACKGROUND: Epistasis has been historically used to describe the phenomenon that the effect of a given gene on a phenotype can be dependent on one or more other genes, and is an essential element for understanding the association between genetic and phenotypic variations. Quantifying epistasis of or...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Ting, Chen, Yuanzhu, Kiralis, Jeff W, Collins, Ryan L, Wejse, Christian, Sirugo, Giorgio, Williams, Scott M, Moore, Jason H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Focus on Translational Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721169/
https://www.ncbi.nlm.nih.gov/pubmed/23396514
http://dx.doi.org/10.1136/amiajnl-2012-001525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721169/
https://www.ncbi.nlm.nih.gov/pubmed/23396514
http://dx.doi.org/10.1136/amiajnl-2012-001525

Ejemplares similares