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An information-gain approach to detecting three-way epistatic interactions in genetic association studies

BACKGROUND: Epistasis has been historically used to describe the phenomenon that the effect of a given gene on a phenotype can be dependent on one or more other genes, and is an essential element for understanding the association between genetic and phenotypic variations. Quantifying epistasis of or...

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Detalles Bibliográficos
Autores principales:	Hu, Ting, Chen, Yuanzhu, Kiralis, Jeff W, Collins, Ryan L, Wejse, Christian, Sirugo, Giorgio, Williams, Scott M, Moore, Jason H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2013
Materias:	Focus on Translational Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721169/ https://www.ncbi.nlm.nih.gov/pubmed/23396514 http://dx.doi.org/10.1136/amiajnl-2012-001525

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