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Gene expression profiling identifies different sub-types of retinoblastoma

BACKGROUND: Mutation of the RB1 gene is necessary but not sufficient for the development of retinoblastoma. The nature of events occurring subsequent to RB1 mutation is unclear, as is the retinal cell-of-origin of this tumour. METHODS: Gene expression profiling of 21 retinoblastomas was carried out...

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Detalles Bibliográficos
Autores principales: Kapatai, G, Brundler, M-A, Jenkinson, H, Kearns, P, Parulekar, M, Peet, A C, McConville, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721394/
https://www.ncbi.nlm.nih.gov/pubmed/23756868
http://dx.doi.org/10.1038/bjc.2013.283