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TERT promoter mutations in ocular melanoma distinguish between conjunctival and uveal tumours

BACKGROUND: Recently, activating mutations in the TERT promoter were identified in cutaneous melanoma. We tested a cohort of ocular melanoma samples for similar mutations. METHODS: The TERT promoter region was analysed by Sanger sequencing in 47 uveal (ciliary body or choroidal) melanomas and 38 con...

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Detalles Bibliográficos
Autores principales: Griewank, K G, Murali, R, Schilling, B, Scholz, S, Sucker, A, Song, M, Süsskind, D, Grabellus, F, Zimmer, L, Hillen, U, Steuhl, K-P, Schadendorf, D, Westekemper, H, Zeschnigk, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721405/
https://www.ncbi.nlm.nih.gov/pubmed/23799844
http://dx.doi.org/10.1038/bjc.2013.312