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Functional and cancer genomics of ASXL family members

Additional sex combs-like (ASXL)1, ASXL2 and ASXL3 are human homologues of the Drosophila Asx gene that are involved in the regulation or recruitment of the Polycomb-group repressor complex (PRC) and trithorax-group (trxG) activator complex. ASXL proteins consist of ASXN, ASXH, ASXM1, ASXM2 and PHD...

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Detalles Bibliográficos
Autor principal: Katoh, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721406/
https://www.ncbi.nlm.nih.gov/pubmed/23736028
http://dx.doi.org/10.1038/bjc.2013.281