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ERBB4 confers metastatic capacity in Ewing sarcoma

Metastatic spread is the single-most powerful predictor of poor outcome in Ewing sarcoma (ES). Therefore targeting pathways that drive metastasis has tremendous potential to reduce the burden of disease in ES. We previously showed that activation of the ERBB4 tyrosine kinase suppresses anoikis, or d...

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Detalles Bibliográficos
Autores principales: Mendoza-Naranjo, Ariadna, El-Naggar, Amal, Wai, Daniel H, Mistry, Priti, Lazic, Nikola, Ayala, Fernanda Rocha Rojas, da Cunha, Isabela Werneck, Rodriguez-Viciana, Pablo, Cheng, Hongwei, Tavares Guerreiro Fregnani, Jose H, Reynolds, Patrick, Arceci, Robert J, Nicholson, Andrew, Triche, Timothy J, Soares, Fernando A, Flanagan, Adrienne M, Wang, Yuzhuo Z, Strauss, Sandra J, Sorensen, Poul H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721475/
https://www.ncbi.nlm.nih.gov/pubmed/23681745
http://dx.doi.org/10.1002/emmm.201202343